To replace the hub/bearing assembly on a 2007 Acura MDX, first loosen the drive axle/hub nut and wheel lug nuts. Raise the vehicle and support it on jack stands. Remove the wheel, brake caliper, bracket, and disc. Remove the drive axle/hub nut and the hub/bearing assembly mounting bolts. Extract the hub/bearing assembly from the 
Steering Knuckle, using a puller if needed. Ensure the mounting surface and drive axle splines are smooth before installing the new assembly. Lubricate the splines, install the assembly, and tighten the bolts in a criss-cross pattern. Install a new drive axle/hub nut loosely. Reinstall the brake disc, bracket, and caliper, then the wheel. Lower the vehicle and tighten the drive axle/hub nut and lug nuts to the correct torque.